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RESEARCH | CURRICULUM VITAE | PUBLICATIONS      

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Name:  SHARMILA SENGUPTA 

Email:   ssg1

Present Position:  Professor

Highest educational Qualification:  Ph.D.

 

Publications:

 

Sengupta S and Bhattacharjee S.B., Induction of repair functions by hydrogen peroxide in Chinese hamster cells, Int. J. Radiat. Biol., 1988 Jun;53(6):935-42


Sengupta (Das Gupta) S and Bhattacharjee, S.B., Effect of low dose hydrogen peroxide treatment of V79 cells in killing and mutation by different agents, Mutation Res. 1990 Feb;243(2):81-5


Chaudhuri S, Sengupta S, Bhattacharyya N. P. and Bhattacharjee S.B., Effect of hydrogen peroxide on mammalian chromatin: Electron microscopic studies, J. Electron Microse., 1992 Aug;41(4):261-3.


Roy (Pal), M, Sengupta S, Bhattacharyya N. P., Dey S.K. and Bhattacharjee S.B., Response of MTX-resistant V79 cells to some DNA damaging agents. 1993 Feb;285(2):199-207.


Roy (Pal) M., Sengupta S, Ghosh R, Bhattacharyya N. P., Dey S. K. and Bhattacharyya S. B., Characterisation of MTX- resistant clones. 1993 Feb;291(1):43-51.


Sengupta S and Bhattacharyya N. P., Oxidative stress induced resistance in Chinese hamster V79 cells. 1996 Nov 12;228(2):267-71.


Ghosh R, Sengupta S and Bhattacharyya N.P., Induction of apoptosis by ionising radiation in Chinese hamster V79 cells and a radioresistant cell strain derived from V79. Ind. J. Expt. Biol., 1996 Sep;34(9):863-7.


Sengupta S and Bhattacharyya N.P. (1996). Possible role of glutathione in resistance to heavy metals and hydrogen peroxide in a radioresistant Chinese hamster V79 cell strain. Ind. J. Expt. Biol., 1996 Sep;34(9):905-8.


Sengupta S, Roy M and Bhattacharyya N.P. (2000). Effect of post AK-2123 treatment in aerobic condition on radiation induced cell killing in V79 cells and a radioresistant cell strain M5 derived from V79 cells. International Association for the Sensitisation of Cancer Treatment (IASCT): Scientific report 2000 (www.macnet.or.jp/pa/iasct/sr_sengupta.html).


Sengupta D, Duttagupta C, Bandyopadhay S, Jana R, Das Sarma J, Sengupta S, and Ray M., An exploratory statistical analysis of the effect of demographic risk factors on uterine cervical squamous intraepithelial lesions. Calcutta Statistical Association Bulletin (Golden Jubilee Issue), 2000, 50, 307- 324. 


Ray M, Sengupta S, Bhattacharya P and Duttagupta C., Human papillomavirus and uterine cervical cancer: state of the art. Science and Culture, 2002 67, 205-211.


Bhattacharya P, Duttagupta C and Sengupta S., Proline homozygosity in codon 72 of p53: a risk genotype for human papillomavirus related cervical cancer in Indian women. Cancer Lett., 2002 Dec 15;188(1-2):207-11.


Duttagupta C, Sengupta S, Roy M, Sengupta D, Chakraborty S, Bhattacharya P, Roy S and Ghosh S., Oncogenic human papillomavirus (HPV) infection and uterine cervical cancer: a screening strategy in the perspective of rural India. Eur J Cancer Prev. 2002 Oct;11(5):447-56.


Chaudhuri K, Bannerjee R, Pandit B, Mukherjee A, Sengupta S, Roychoudhury S, and Bhattacharyya, N. P., Identification of two differentially expressed mitochondrial genes in a methotrexate resistant Chinese hamster cell strain derived from V79 cells using RNA fingerprinting by arbitrarily primed polymerase chain reaction (RAP- PCR). Radiat Res. 2003 Jul;160(1):77-85.


Duttagupta C, Sengupta S, Roy M, Sengupta D, Bhattacharya P, Laikangbam P, Roy S, Ghosh S and Das R., Are Muslim women less susceptible to oncogenic human papillomavirus Infection? : A study from rural eastern India. Int J Gynecol Cancer. 2004 Mar-Apr;14(2):293-303.


Bhattacharya P and Sengupta S., HLA DQB1*03 genotypes and susceptibility to cervical cancer in Indian women. Int J Hum Genet, 2005, 5, 21-27.


Bhattacharya P and Sengupta S., Lack of evidence that proline homozygosity at codon 72 of p53 and rare arginine allele at codon 31 of p21 jointly mediate cervical cancer susceptibility among Indian women. Gynecol Oncol. 2005 Oct;99(1):176-82.


Bhattacharjee B and Sengupta S., HPV16 E2 gene disruption and polymorphisms of E2 and LCR: some significant associations with cervical cancer in Indian women. Gynecol Oncol. 2006 Feb;100(2):372-8 [Epub 2005 Oct 24].


Bhattacharya P, Shankarkumar U and Sengupta S., HLA B*1301 and B*1801 alleles are positively associated with HPV related cervical cancer in women from Kolkata, Eastern India. Int J Hum Genet. 2006, 6, 139-144.


Bhattacharjee B and Sengupta S., CpG methylation of HPV 16 LCR at E2 binding site proximal to P97 is associated with cervical cancer in presence of intact E2. Virology. 2006 Oct 25;354(2):280-5 [Epub 2006 Aug 14].


Laikangbam P, Sengupta S, Bhattacharya P, Duttagupta C, Singh D, Verma Y, Roy S, Das R and Mukhopadhyay M., A comparative profile of the prevalence and age-distribution of human papillomavirus type 16/18 infections among three states of India with focus on Northeast India. Int J Gynecol Cancer. 2007 Jan-Feb;17(1):107-17.


Bhattacharya P and Sengupta S., Predisposition to HPV16/18-related cervical cancer because of proline homozygosity at codon 72 of p53 among Indian women is influenced by HLA-B*07 and homozygosity of HLA-DQB1*03. Tissue Antigens. 2007 Oct;70(4):283-93.
Bhattacharjee B, Mandal N.R., Roy S and Sengupta S., Characterisation of sequence variations within HPV16 isolates among Indian women: prediction of causal role of rare non-synonymous variations within intact isolates in cervical cancer pathogenesis. Virology. 2008 Jul 20;377(1):143-50. doi: 10.1016/j.virol.2008.04.007 [Epub 2008 May 20].

Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna S MF, Ciotti M, Das BR, Del Mistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws ALF, Helland A, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J, Ngan HYS, Nishikawa A, Niwa Y, Pegoraro R, Pillai MR, Ranzani G, Rezza G, Rosenthal AN, Roychoudhury S, Saranath D, Schmitt VM, Sengupta S, Settheetham-Ishida W, Shirasawa H, Snijders PJF, Stoler MH, Suárez-Rincón AE, Szarka K, Tachezy R, Ueda M, van der Zee AGJ, von Knebel Doeberitz M, Wu M, Yamashita T, Zehbe I, Blettner M., TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies. Lancet Oncol. 2009 Aug;10(8):772-84. [doi: 10.1016/S1470-2045(09)70187-1. Epub 2009 Jul 20].


Das D, Bhattacharjee B, Sen S, Mukhopadhyay I and Sengupta S., Association of viral load with HPV16 positive cervical cancer pathogenesis: causal relevance in isolates harbouring intact viral E2 gene. Virology. 2010 Jun 20;402(1):197-202. [doi: 10.1016/j.virol.2010.03.030. Epub 2010 Apr 14].


Sarkar K, Pal R, Bal B, Saha B, Bhattacharya S, Sengupta S, Majumder PP and Chakraborti S., Oncogenic HPV among HIV infected female population in West Bengal, India. BMC BMC Infect Dis. 2011 Mar 22;11:72. [doi: 10.1186/1471-2334-11-72].


Das D, Bhattacharjee B, Sen S, Laikangbam P, Mukhopadhyay I, Roy Chowdhury R, Roy S and Sengupta S (2012).  Some novel insights on HPV16 related cervical cancer pathogenesis based on analyses of LCR methylation, viral load, E7 and E2/E4 expressions. PLoS One. 2012;7(9):e44678. [doi: 10.1371/journal.pone.0044678. Epub 2012 Sep 6].


Mandal P, Bhattacharjee B, Das Ghosh D, Mondal N.R., Roy Chowdhury R, Roy S and Sengupta S (2013).  Differential expression of HPV16 L2 gene in cervical cancers harboring episomal HPV16 genomes: influence of synonymous and non-coding region variations. PLoS ONE 8(6): e65647. doi:10.1371/journal.pone.0065647.


Ghosh P, Das Ghosh D, Majumdar (Giri) A, Sengupta S, Chandana Das, and Indranil Mukhopadhyay (2014). Polymerase chain reaction and deoxyribonucleic acid-sequencing based study on distribution of human papillomavirus 16/18 among histopathological types of cervical intra-epithelial neoplasia and primary invasive cervical carcinoma: A scenario in North Bengal, India. Journal of Mid-life Health, 5: 14-22.


Sharma S, Mandal P, Sadhukhan T, Roy Chowdhury R, Mondal N.R., Chakravarty B, Chatterjee T, Roy S and Sengupta S (2015).  Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis. Scientific Reports 5:11724/DOI: 10.1038/srep11724.


*Mandal, P., * #Bhattacharjee B . , Sen, S., Bhattacharya A., Roy Chowdhury, R., Mondal, N. R., and #Sengupta, S . Complete genome sequences of eight Human Papillomavirus type 16 Asian American and European variant isolates from cervical biopsies and lesions in Indian women. Genome Announcements (2016) 4(3) e00243-16.


Saha Sharma, S., Roy Chowdhury, R., Mondal, N.R., Chakravarty, B., Chatterjee, T., Roy, S., and Sengupta, S. (2016). Identification of genetic variation in the lncRNA HOTAIR associated with HPV16-related cervical cancer pathogenesis. Cellular Oncology 39, 559-572.


Saha Sharma, S., Roy Chowdhury, R., Mandal, N.R., Roy, S.,and Sengupta, S (2017). Expression signatures of HOX cluster genes in cervical cancer pathogenesis: Impact of human papillomavirus type 16 oncoprotein E7. Oncotarget, DOI: 10.18632/oncotarget.16619 (Advance Publication). [Impact Factor 5.008].


Das Ghosh, D., Mukhopadhyay, I., Bhattacharya, A., Roy Chowdhury, R., Mandal, N.R., Roy, S.,and Sengupta, S (2017). Impact of genetic variations and transcriptional alterations of HLA class I genes on cervical cancer pathogenesis. International Journal of Cancer, DOI: 10.1002/ijc.30681 (epub ahead of publication).


Sen S., Mandal P., Bhattacharya A., R., Mondal, N.R., Chakravarty, B., Chatterjee, T., Roy, S., and Sengupta, S. (2017). Impact of viral and host DNA methylations on HPV16-related cervical cancer pathogenesis. Tumor Biology, DOI: 10.1177/1010428317699799 journals.sagepub.com/home/tub

 

#co-corresponding authors