BRIC-NIBMG | BRIC National Institute of Biomedical Genomics

LncRNA CASC19 promotes pancreatic cancer progression by increasing PSPC1 protein stability and facilitating the oncogenic PSPC1/ β-Catenin pathway.

Mukherjee M, Ghosh S, Maity A, Ray S, Saha H, Bahadur RP, Goswami S. Mol Med. 2025 Sep 29;31(1):305. doi: 10.1186/s10020-025-01363-7. PMID: 41023804; PMCID: PMC12482102.
Examining Transcriptomic Markers Associated With Neutrophil Extracellular Traps to Predict Mortality Risk in Neonatal Sepsis.

Shaw D, Santhanam S, Som TK, Bhattacharjee S, Mohapatra SK. Open Forum Infect Dis. 2025 Sep 24;12(9):ofaf570. doi: 10.1093/ofid/ofaf570. PMID: 41001617
JMJD6 and YBX1 physically interact and regulate HOTAIR proximal promoter

Gupta A, Bhardwaj S, Desai KV. Biochem J. 2025 Sep 4;482(17):1289-1305. doi: 10.1042/BCJ20243020. PMID: 40855961.
Impact of an Integrated Intervention Package During Preconception, Pregnancy, and Early Childhood on the Gut Microbiome at Six Months of Age: Findings from the Women and Infants Integrated Growth Study (WINGS) Randomized Controlled Trial

Chowdhury R, Maddheshiya A, Taneja S, Bhandari N, Majumder PP, Strand TA, Pandey RM, Kurpad AV, Mukherjee S. J Nutr. 2025 Jul;155(7):2355-2366. doi: 10.1016/j.tjnut.2025.04.016. PMID: 40615170.
Comprehensive genomic and digital pathology profiling of tobacco-chewer female oral cancer patients simultaneously with integration of single-cell datasets identifies clinically actionable patient subgroups

Ghosh A, Singh S, Mallick TR, Chakravarty S, Varsha Bhagat S, Das C, Gopinath KS, Mohiyuddin A, Maitra A, Majumder PP, Kundu TK, Biswas NK. Clin Transl Med. 2025 Jul;15(7):e70386. doi: 10.1002/ctm2.70386. PMID: 40621643.
Long-term arsenic exposure perturbs gut microbial diversity, composition and predicts metabolic dysregulation

Ghosh S., Nath S., Chakraborty A., Bhowmick S. , Majumdar K.K. , Mukherjee S., Pramanik S.; Journal of Hazardous Materials, 2025, 138836, ISSN 0304-3894, https://doi.org/10.1016/j.jhazmat.2025.138836.
Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients

Mitra P, Saha U, Stephen KJ, Prasad P, Jena S, Patel AK, Bv H, Mondal SK, Kurkalang S, Roy S, Ghosh A, Roy SS, Das Sarma J, Biswas NK, Acharya M, Sharan R, Arun P, Jolly MK, Maitra A, Singh S. J Exp Clin Cancer Res. 2025 May 10;44(1):142. doi: 10.1186/s13046-025-03405-8. PMID: 40349056.
Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer.

Roy, J., Kumar, A., Chakravarty, S., Biswas, N. K., Goswami, S., & Mazumder, A. EMBO reports, 0(0), 1-26. https://doi.org/https://doi.org/10.1038/s44319-025-00446-0
Mapping genetic diversity with the GenomeIndia project.

Chandrika Bhattacharyya, Krithika Subramanian, Bharathram Uppili, Nidhan K. Biswas, Shweta Ramdas, Karthik Bharadwaj Tallapaka, Prathima Arvind, Khader Valli Rupanagudi, Arindam Maitra, Tulasi Nagabandi, Tiyasha De, Kuldeep Singh, Praveen Sharma, Nanaocha Sharma, Sunil K. Raghav, Punit Prasad, E. V. Soniya, Abdul Jaleel, Shijulal Nelson Sathi, Madhvi Joshi, Chaitanya Joshi, Mayurika Lahiri, Santosh Dixit, L. S. Shashidhara, Nachimuthu Senthil Kumar, H. Lalhruaitluanga, Lal Nundanga, Venkataram Shivakumar, Ganesan Venkatasubramanian, Naren P. Rao, Mohd Ashraf Ganie, Imtiyaz Ahmad Wani, Ganganath Jha, Ashwin Dalal, Murali Dharan Bashyam, Pritish Kumar Varadwaj, SanjeevBS, Yogesh Simmhan, Chirag Jain, Durai Sundar, Ishaan Gupta, Pankaj Yadav, Himanshu Sinha, Manikandan Narayanan, Karthik Raman, Raghu Padinjat, Radhakrishnan Sabarinathan, GenomeIndia Consortium, Yadati Narahari, Vijayalakshmi Ravindranath, Thangaraj Kumarasamy, Divya Tej Sowpati, Mohammed Faruq, Analabha Basu & Bratati KahaliNat Genet (2025). https://doi.org/10.1038/s41588-025-02153-x
Uncovering the Role of Tertiary Lymphoid Organs in the Inflammatory Landscape: A Novel Immunophenotype of Diabetic Foot Ulcers

Banerjee D, Paul S, Selvan C, Pai S, Nandakumar BS, Mukherjee S, Raghavendra PB. J Cell Mol Med. 2025 Apr;29(7):e70479. doi: 10.1111/jcmm.70479. PMID: 40159626.

Research Spotlight

LncRNA CASC19 promotes pancreatic cancer progression by increasing PSPC1 protein stability and facilitating the oncogenic PSPC1/ β-Catenin pathway.

Mukherjee M, Ghosh S, Maity A, Ray S, Saha H, Bahadur RP, Goswami S. Mol Med. 2025 Sep 29;31(1):305. doi: 10.1186/s10020-025-01363-7. PMID: 41023804; PMCID: PMC12482102.

Examining Transcriptomic Markers Associated With Neutrophil Extracellular Traps to Predict Mortality Risk in Neonatal Sepsis.

Shaw D, Santhanam S, Som TK, Bhattacharjee S, Mohapatra SK. Open Forum Infect Dis. 2025 Sep 24;12(9):ofaf570. doi: 10.1093/ofid/ofaf570. PMID: 41001617

JMJD6 and YBX1 physically interact and regulate HOTAIR proximal promoter

Gupta A, Bhardwaj S, Desai KV. Biochem J. 2025 Sep 4;482(17):1289-1305. doi: 10.1042/BCJ20243020. PMID: 40855961.

Impact of an Integrated Intervention Package During Preconception, Pregnancy, and Early Childhood on the Gut Microbiome at Six Months of Age: Findings from the Women and Infants Integrated Growth Study (WINGS) Randomized Controlled Trial

Chowdhury R, Maddheshiya A, Taneja S, Bhandari N, Majumder PP, Strand TA, Pandey RM, Kurpad AV, Mukherjee S. J Nutr. 2025 Jul;155(7):2355-2366. doi: 10.1016/j.tjnut.2025.04.016. PMID: 40615170.

Comprehensive genomic and digital pathology profiling of tobacco-chewer female oral cancer patients simultaneously with integration of single-cell datasets identifies clinically actionable patient subgroups

Ghosh A, Singh S, Mallick TR, Chakravarty S, Varsha Bhagat S, Das C, Gopinath KS, Mohiyuddin A, Maitra A, Majumder PP, Kundu TK, Biswas NK. Clin Transl Med. 2025 Jul;15(7):e70386. doi: 10.1002/ctm2.70386. PMID: 40621643.

Long-term arsenic exposure perturbs gut microbial diversity, composition and predicts metabolic dysregulation

Ghosh S., Nath S., Chakraborty A., Bhowmick S. , Majumdar K.K. , Mukherjee S., Pramanik S.; Journal of Hazardous Materials, 2025, 138836, ISSN 0304-3894, https://doi.org/10.1016/j.jhazmat.2025.138836.

Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients

Mitra P, Saha U, Stephen KJ, Prasad P, Jena S, Patel AK, Bv H, Mondal SK, Kurkalang S, Roy S, Ghosh A, Roy SS, Das Sarma J, Biswas NK, Acharya M, Sharan R, Arun P, Jolly MK, Maitra A, Singh S. J Exp Clin Cancer Res. 2025 May 10;44(1):142. doi: 10.1186/s13046-025-03405-8. PMID: 40349056.

Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer.

Roy, J., Kumar, A., Chakravarty, S., Biswas, N. K., Goswami, S., & Mazumder, A. EMBO reports, 0(0), 1-26. https://doi.org/https://doi.org/10.1038/s44319-025-00446-0

Mapping genetic diversity with the GenomeIndia project.

Uncovering the Role of Tertiary Lymphoid Organs in the Inflammatory Landscape: A Novel Immunophenotype of Diabetic Foot Ulcers

Banerjee D, Paul S, Selvan C, Pai S, Nandakumar BS, Mukherjee S, Raghavendra PB. J Cell Mol Med. 2025 Apr;29(7):e70479. doi: 10.1111/jcmm.70479. PMID: 40159626.