BRIC-NIBMG | BRIC National Institute of Biomedical Genomics

An ensemble machine learning-based performance evaluation identifies top In-Silico pathogenicity prediction methods that best classify driver mutations in cancer.

Das S, Patel V, Chakravarty S, Ghosh A, Mukhopadhyay A, Biswas NK. BioData Min. 2025 Jan 20;18(1):7. doi: 10.1186/s13040-024-00420-x. PMID: 39833905.
An insight into COVID-19 host immunity at single-cell resolution

Ghosh, S., Chatterjee, A., & Maitra, A. 2024. International reviews of immunology, 1–16. Advance online publication. https://doi.org/10.1080/08830185.2024.2443420
Regulation of pathway choice in DNA repair after double-strand breaks.

Kumari, N., Kaur, E., Raghavan, S. C., & Sengupta, S. 2024; Current opinion in pharmacology, 80, 102496. Advance online publication. https://doi.org/10.1016/j.coph.2024.102496
Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma

Chakraborty, S., Sarma, J., Roy, S. S., Mitra, S., Bagchi, S., Das, S., Saha, S., Mahapatra, S., Bhattacharjee, S., Maulik, M., & Acharya, M. 2024; PLoS genetics, 20(12), e1011502. https://doi.org/10.1371/journal.pgen.1011502
Deep learning insights into distinct patterns of polygenic adaptation across human populations.

Tripathi D, Bhattacharyya C, Basu A. Nucleic Acids Res. 2024 Nov 21:gkae1027. doi: 10.1093/nar/gkae1027.
Previse preterm birth in early pregnancy through vaginal microbiome signatures using metagenomics and dipstick assays

Talukdar, D., Sarkar, M., Ahrodia, T., Kumar, S., De, D., Nath, S., Jana, P., Verma, J., Mehta, O., Kothidar, A., Yodhaanjali, J. R., Sharma, K., Bakshi, S., Singh, U., Kshetrapal, P., Wadhwa, N., Thiruvengadam, R., Garbh-Ini study group, Nair, G. B., Bhatnagar, S., Mukherjee S, Das, B. iScience. 2024 Oct 23;27(11):111238. doi: 10.1016/j.isci.2024.111238. eCollection 2024 Nov 15.
Neurotropic Murine β-Coronavirus Infection Causes Differential Expression of Connexin 47 in Oligodendrocyte Subpopulations Associated with Demyelination.

Das S, Shaw AK, Das Sarma S, Koval M, Das Sarma J, Maulik M. Mol Neurobiol. 2024 Sep 18. doi: 10.1007/s12035-024-04482-0.
Multi-regional genomic and transcriptomic characterization of a melanoma-associated oral cavity cancer provide evidence for CASP8 alteration-mediated field cancerization.

Chakravarty S, Ghosh A, Das C, Das S, Patra S, Maitra A, Ghose S, Biswas NK. Hum Genomics. 2024 Sep 7;18(1):96. doi: 10.1186/s40246-024-00668-8.
Biological and clinical relevance of correlated expression levels of coding and long noncoding RNAs in HPV16 positive cervical cancers.

Hum Genomics. 2024 Aug 29;18(1):91. doi: 10.1186/s40246-024-00660-2. PMID: 39210444; PMCID: PMC11360852.
Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants

Nat Commun. 2024 Aug 14;15(1):6985. doi: 10.1038/s41467-024-51075-5. PMID: 39143063; PMCID: PMC11324957.

Research Spotlight

An ensemble machine learning-based performance evaluation identifies top In-Silico pathogenicity prediction methods that best classify driver mutations in cancer.

Das S, Patel V, Chakravarty S, Ghosh A, Mukhopadhyay A, Biswas NK. BioData Min. 2025 Jan 20;18(1):7. doi: 10.1186/s13040-024-00420-x. PMID: 39833905.

An insight into COVID-19 host immunity at single-cell resolution

Ghosh, S., Chatterjee, A., & Maitra, A. 2024. International reviews of immunology, 1–16. Advance online publication. https://doi.org/10.1080/08830185.2024.2443420

Regulation of pathway choice in DNA repair after double-strand breaks.

Kumari, N., Kaur, E., Raghavan, S. C., & Sengupta, S. 2024; Current opinion in pharmacology, 80, 102496. Advance online publication. https://doi.org/10.1016/j.coph.2024.102496

Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma

Chakraborty, S., Sarma, J., Roy, S. S., Mitra, S., Bagchi, S., Das, S., Saha, S., Mahapatra, S., Bhattacharjee, S., Maulik, M., & Acharya, M. 2024; PLoS genetics, 20(12), e1011502. https://doi.org/10.1371/journal.pgen.1011502

Deep learning insights into distinct patterns of polygenic adaptation across human populations.

Tripathi D, Bhattacharyya C, Basu A. Nucleic Acids Res. 2024 Nov 21:gkae1027. doi: 10.1093/nar/gkae1027.

Previse preterm birth in early pregnancy through vaginal microbiome signatures using metagenomics and dipstick assays

Neurotropic Murine β-Coronavirus Infection Causes Differential Expression of Connexin 47 in Oligodendrocyte Subpopulations Associated with Demyelination.

Das S, Shaw AK, Das Sarma S, Koval M, Das Sarma J, Maulik M. Mol Neurobiol. 2024 Sep 18. doi: 10.1007/s12035-024-04482-0.

Multi-regional genomic and transcriptomic characterization of a melanoma-associated oral cavity cancer provide evidence for CASP8 alteration-mediated field cancerization.

Chakravarty S, Ghosh A, Das C, Das S, Patra S, Maitra A, Ghose S, Biswas NK. Hum Genomics. 2024 Sep 7;18(1):96. doi: 10.1186/s40246-024-00668-8.

Biological and clinical relevance of correlated expression levels of coding and long noncoding RNAs in HPV16 positive cervical cancers.

Hum Genomics. 2024 Aug 29;18(1):91. doi: 10.1186/s40246-024-00660-2. PMID: 39210444; PMCID: PMC11360852.

Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants

Nat Commun. 2024 Aug 14;15(1):6985. doi: 10.1038/s41467-024-51075-5. PMID: 39143063; PMCID: PMC11324957.