National Institute Of Biomedical Genomics (NIBMG) National Institute Of Biomedical Genomics National Institute Of Biomedical Genomics

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Name: Samsiddhi Bhattacharjee

Email:
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Present Position: Assistant Professor

Highest Educational Qualification: Ph.D.

Past Appointments:

  • Research Fellow, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , USA

Awards & Honours:

  • Statistics in Epidemiology Young Investigator Award (Joint Statistical Meetings, 2010).

 

Research Interests:

  • Genetic association, Gene-Gene and Gene-Environment interactions using family or case-control data.
  • Meta-analysis of omics studies.
  • Pathway analysis: omnibus and interaction tests.
  • Gene-Set and other Enrichment Analyses.
  • Complex traits and complex environmental exposures.
  • Multiple Testing Issues and Exploratory Data Analysis.

 

Current Projects:

  • Subset-based meta-analysis in presence of heterogeneity
  • Generalized conditional and unconditional score tests for family-based association
  • Pathway analysis of one-carbon pathway in pancreatic cancer
  • Analysis of GWAS data on cancers
Past Major Projects:
  • CGEN (Case-Control Genetics): Development of R package CGEN implementing various methods for analysis of case-control data in genetic epidemiology studies. (http://www.bioconductor.org/help/bioc-views/release/bioc/html/CGEN.html).
  • Methods for detecting Gene-Gene interactions in a GWAS in presence of population stratification: Development of robust and powerful methods and comparison with existing methods for detecting gene-gene interactions in genome-wide association studies in presence of hidden population substructure.
  • Score statistics for QTL association analysis: Development of conditional score statistics for association analysis of quantitative traits in families and comparison with existing family-based association methods. (With Dr. Eleanor Feingold, Univ. of Pittsburgh ).
  • QTL-ALL: QTL Analysis and Linkage Library: Development of user friendly software for QTL mapping statistics .
  • Robust score statistics for QTL linkage analysis: Development of robust score statistic variants for linkage analysis and simulation study of existing and novel variants.
  • Optimal pedigree weights for NPL statistics: Choice of optimal pedigree weights for non-parametric linkage statistics and comparison of standard weighting schemes
  • Reverse Regression approach for mapping Multivariate Phenotypes: A novel approach for multivariate QTL linkage analysis for sibship data and application to linkage mapping of GAW 14 data on Kofendrerd Personality Disorder.

List of Publications

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NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS, Netaji Subhas Sanatorium (T.B. Hospital), 2nd Floor P.O.: N.S.S., Kalyani 741251, West-Bengal, INDIA