Sepsis is a rapidly progressing condition associated with high morbidity and mortality. There is a need to find strong and reliable markers that can serve to stratify patients and alert clinicians to impending complications. The primary objective of this study is to find molecular patterns in blood of the patients at early stage of disease that can be predictive of late clinical outcome.
Bassaganya-Riera J, Dominguez-Bello MG, Kronsteiner B, Carbo A, Lu P, Viladomiu M, Pedragosa M, Zhang X, Sobral BW, Mane SP, MOHAPATRA SK, et al. (2012) Helicobacter pylori colonization ameliorates glucose homeostasis in mice through a PPAR γ-dependent mechanism. PLOS One. 2012;7(11):e50069.
MOHAPATRA SK and Krishnan A. (2011) Microarray Data Analysis. Methods Mol Biol. 678:27
MOHAPATRA SK, Cole LE, Evans C, Sobral BW, Bassaganya-Riera J, Hontecillas R, Vogel SN, Crasta OR. (2010) Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection. BMC Infect Dis. 10:10.
Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, MOHAPATRA SK, Crasta OR, Vogel SN, Cross AS, Hassel BA. (2008) An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity. Proc Natl Acad Sci U S A. 105:20816-20821.
Chatterjee M, MOHAPATRA S, Ionan A, Bawa G, Ali-Fehmi R, Wang X, Nowak J, Ye B, Nahhas FA, Lu K, Witkin SS, Fishman D, Munkarah A, Morris R, Levin NK, Shirley NN, Tromp G, Abrams J, Draghici S, Tainsky MA. (2006) Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Res. 66(2):1181-1190.